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GenAI4EU: Funding opportunities to boost Generative AI “made in Europe”

The European Commission has launched a first wave of EU funding opportunities to integrate generative Artificial Intelligence (AI) in Europe’s strategic sectors, and keep their competitive edge.

Researchers, innovators, companies and other interested organisations can find broad EU funding opportunities to join forces to develop and deploy generative AI in Europe’s strategic sectors as part of the GenAI4EU flagship initiative. The initiative is now surpassing the initial commitment of €500 million announced in the AI innovation package in January 2024, with close to €700 million funding planned in Horizon Europe, the Digital Europe Programme, and the European Innovation Council.

For example, researchers can receive EU funding of between 15 and 17 million euro to leverage multimodal data to advance generative AI in biomedical research by, among others, moving towards predictive and personalised medicine. This concrete GenAI application helps industry’s competitiveness but also makes healthcare treatments more effective. The call HORIZON-HLTH-2025-01-TOOL-03 will close in September 2025.

This is only one of the many opportunities available to stakeholders interested in joining the GenAI4EU initiative, as listed on the tab "funding opportunities".

 

The European Commission has launched a first wave of EU funding opportunities to integrate generative Artificial Intelligence (AI) in Europe’s strategic sectors, and keep their competitive edge. The table below gives an overview of relevant calls from the Horizon Europe Work Programme 2025, including the European Innovation Council, and the Digital Europe Programme. All topics contribute to GenAI4EU. Future calls will also be found on the EU’s Funding & Tenders Portal. Stakeholders are encouraged to use the b2match platform for networking and matchmaking. Support in the application process is offered by Ideal-Ist.

Ongoing calls

Horizon Europe cluster 

Title of the call

Timing

Cluster 5 (Energy)

HORIZON-CL5-2025-02-D3-19: Innovative solutions for a Generative AI-powered digital spine of the EU energy system 16 September 2025 – 17 February 2026

Cluster 5 (Mobility)

HORIZON-CL5-2025-01-D6-08: Accelerating freight transport and logistics digital innovation 16 September 2025 - 20 January 2026

Cluster 5 (Mobility)

HORIZON-CL5-2025-01-D2-05: Accelerated multi-physical and virtual testing for battery aging, reliability, and safety evaluation (Batt4EU Partnership) 16 September 2025 - 20 January 2026

Cluster 5 (Mobility)

HORIZON-CL5-2026-01-D6-09: Reliable data and practices to measure and account transport emissions in multimodal transport chains 16 September 2025 - 20 January 2026

Cluster 5 (Mobility)

HORIZON-CL5-2026-01-D6-10: Integrating inland waterway transport in smart shipping and multimodal logistics chains 16 September 2025 - 20 January 2026

Cluster 6 (Agrifood)

HORIZON-CL6-2025-01-CIRCBIO-01-two-stage: Open Topic: Innovative solutions for the sustainable and circular transformation of SMEs 4 September 2025 – 18 February 2026

Digital Europe Programme Work Programme 2025-27: GenAI4EU calls

Strategic Objective

Title of the call

Call timing

SO2

DIGITAL-2026-AI-09-GENAI-PA: Apply AI: GenAI for the public administrations 4 November 2025 – 3 March 2026

SO2

4 November 2025 – 3 March 2026

SO2

Testing GenAI4EU applications at scale and under real-world conditions Q1-Q2 2026

SO2

Apply AI: Piloting AI-based image screening in medical centres Q2 – Q3 2026

Past calls

Horizon Europe Work Programme 2025: GenAI4EU calls

Horizon Europe cluster 

Title of the call

Timing

Cluster 1 (Health)

HORIZON-HLTH-2025-01-TOOL-03: GenAI4EU: Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research 22 May – 16 September 2025

Cluster 1 (Health)

HORIZON-HLTH-2025-01-CARE-01: GenAI4EU: End user-driven application of Generative Artificial Intelligence models in healthcare 22 May – 16 September 2025

Cluster 3 (Civil security for society)

HORIZON-CL3-2025-02-EDCC-01: Generative AI for Cybersecurity applications 12 June – 12 November 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-04-DIGITAL-EMERGING-07: Enhanced Learning Strategies for General Purpose AI: Advancing GenAI4EU 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-04-DIGITAL-EMERGING-04: Assessment methodologies for General Purpose AI capabilities and risks 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-03-DIGITAL-EMERGING-09: Challenge-Driven GenAI4EU Booster (Pharma/Telco and Aerospace) 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-03-DIGITAL-EMERGING-07: Robust and trustworthy GenAI4EU in Robotics and industrial automation 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-03-HUMAN-15: GenAI4EU: Generative AI for Virtual Worlds: Advanced technologies for better performance and hyper personalised and immersive experience 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-04-DATA-03: Software Engineering for AI and Generative AI 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-04-DATA-02: Empowering AI/Generative AI along the Cognitive Computing continuum 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-2025-03-DATA-13: Fostering Innovative and Compliant Data Ecosystems 10 June – 2 October 2025

Cluster 4 (Digital, Industry, Space)

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61: AI Foundation models in science (GenAI4EU) 22 May – 23 September 2025

Cluster 5 (Mobility)

HORIZON-CL5-2025-04-D6-01: Advancing remote operations to enable the sustainable and smart mobility of people and goods based on operational and societal needs (CCAM Partnership) – Societal Readiness Pilot 6 May – 4 September 2025

Cluster 5 (Mobility)

HORIZON-CL5-2025-01-D5-01: Efficient wireless stationary bidirectional charging solutions for road Light Duty Vehicles 6 May – 4 September 2025

Cluster 5 (Mobility)

HORIZON-CL5-2025-01-D5-02: Cybersecure and resilient road e-mobility ecosystem 6 May – 4 September 2025

Cluster 6 (Agrifood)

HORIZON-CL6-2025-01-ZEROPOLLUTION-06: Provide digital solutions tailored to small and medium-sized farms to monitor and sustainably manage agricultural inputs and natural resources 6 May – 17 September 2025

Cluster 6 (Agrifood)

HORIZON-CL6-2025-03-GOVERNANCE-09: Delivering Earth Intelligence to accelerate the green and digital transition 6 May – 24 September 2025

Cluster 6 (Agrifood)

HORIZON-CL6-2025-03-GOVERNANCE-14: Preparing farmers, their workforce and advisors to the future of agriculture by providing the right knowledge and skills at the right time and place 6 May – 24 September 2025

Cluster 6 (Agrifood)

HORIZON-CL6-2025-01-CIRCBIO-09: Unleashing the potential and advancing the impact of the digitalisation/AI of the bio-based value chains 6 May – 17 September 2025

Cluster 6 (Agrifood)

HORIZON-CL6-2025-01-BIODIV-08: Strengthening pathways to alternative socio-economic models for continuous improvement of biodiversity 6 May – 17 September 2025

European Innovation Council 2025

 

Title of the call

Call deadline

Accelerator Challenges

GenAI4EU: Creating European Champions in Generative AI 1 October 2025

Pathfinder Challenges

Generative-AI based Agents to Revolutionize Medical Diagnosis and Treatment of Cancer 29 October 2025

Digital Europe Programme Work Programme 2025-27: GenAI4EU calls

Strategic Objective

Title of the call

Call timing

SO2

DIGITAL-2025-AI-08-SUPPLY-AI: GenAI for the public administrations 15 April – 2 October 2025

SO4

DIGITAL-2025-SKILLS-08-GENAI-ACADEMY-STEP: Sectoral digital skills academies: Digital Skills Academy in GenAI 15 April – 2 September 2025

GenAI4EU: moving generative AI from a promising potential to concrete applications

Researchers, innovators, industrial companies and others applying to these EU funding opportunities will become part of GenAI4EU. It is the European Commission’s flagship initiative to support the development and deployment of generative AI solutions across Europe’s industrial ecosystems. 

The specific sectors—manufacturing, robotics, health, energy, agrifood, mobility, and aerospace—are aligned with those identified in the EU Industrial Strategy and the Draghi Report. GenAI4EU will support the transition pathways outlined in these strategies by driving innovation, streamlining production, and fostering sustainable growth in these sectors through the tailored adoption of generative AI. This initiative will promote the development of large, open innovation ecosystems that encourage collaboration between AI developers—including startups and scale-ups—and strategic European industrial players and the public sector.

GenAI4EU sectors

As such, GenAI4EU contributes to the European Commission’s overarching goals of enhancing competitiveness and economic growth through AI, as outlined in the AI Continent Action Plan presented in April 2025 and the Apply AI strategy in October 2025. GenAI4EU aims to increase the adoption of AI among EU companies, which currently stands at just 13.5%. This highlights the significant potential for growth, innovation, and competitiveness through broader AI uptake. 

This initiative builds on the Horizon Europe’s AI Boost project (2023) , which awarded €1 million and 8 million GPU hours to four winners developing large AI models. It also builds on the Digital Europe Programme’s support for open-source, multilingual large language models through OpenEuroLLM . Ongoing efforts aim to embed generative AI in future calls across Horizon Europe, DEP, and the European Innovation Council (EIC) for 2026 and 2027, reinforcing Europe’s position as a global hub for secure, inclusive, and innovative AI technologies.

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The EU is spearheading AI research, collaborating with scientists, and funding projects to achieve excellence in frontier AI and foster AI “made in Europe”.