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OraMod project: Helping clinicians predict oral cavity cancer reoccurrence

  • PROJECTS STORY
  • Publication 20 janvier 2014

Genomic markers and computer models can predict the reoccurance of oral cavity cancer. But these innovative diagnostic technologies are currently stuck in labs and are not being used by clinicians in hospitals. The EU-funded project OraMod, led by the University of Parma, aims to solve this problem by building an IT platform and a diagnostic device.

OraMod logo

OraMod continues the research conducted by the finished FP7-NeoMark project: NeoMark produced a set of prognostic bio-markers and a genetic bio-signature significant for reoccurrence of oral cavity tumors - a disease more and more frequent and with a very high mortality rate.

By adopting the results of the most advanced research in oncology and of technology developments in the fields of genomics, image diagnostics and biostatistical predictive models, the project experts will provide to clinicians a technology platform allowing the early identification of patients at highest risk of bad prognosis.

Analysing data

The platform will be able to analyse tens of thousands clinical, radiology and genomic data for each individual patient. It will be able to detect the patients at high risk for disease reoccurrence, for whom personalised and specific therapeutic approaches will be adopted.

Low-cost identification

An innovative in vitro diagnostic device based on a personalized "lab-on-chip", will allow fast and low-cost identification of genomic predictive markers.

The OraMod project will receive a funding of more than € 3 million throughout three years. It engages 8 partners from 5 European countries, among which:

  • three university hospitals (VU medical center Amsterdam, Heinrich-Heine University Clinic Dusseldorf and the University of Parma with the University Hospital);
  • two primary European research institutions (the Fraunhofer Institute for Computer Graphics IGD Darmstad Germany and the VTT Technology Center of Finland) and;
  • three technology providers (Velti in Greece, OneToNet and STmicroelectronics in Italy).

www.oramod.eu